Beedrill
Bug Lord of the swarm
190 base health
- Signature move
- Pin Missile
- Attacks
- Bursting needles, Take Down, Fan of 3 shots
- Second phase
- Bursting needles, 2 chained charges, Summons 2 Weedle, Volley
PokéIsaac Guide › Bosses
PokéIsaac bosses
Every boss in PokéIsaac 1.0.10: health, signature move, attacks in each phase and the types that hit it super effectively. Classic mode has a boss at the end of every floor, a shiny mega boss every 10 floors and Armored Mewtwo on floor 30.
Pokémon Tower
Gengar
Marowak
Dusknoir
Chandelure
Spiritomb
GengarMarowakDusknoirChandelureSpiritombCerulean Cave
Mewtwo
MewtwoFloor 30
Armored Mewtwo
Armored MewtwoDistortion Room
Darkrai
DarkraiAlso: the 37 mega bosses · Indigo League and Mt. Silver leaders
How boss fights work
- Health on deeper floors
- Base health × 2.5 on floor 10, × 6 on floor 20, × 12 on floor 30
- Bosses adapt to you
- The run rates you as you play: it measures the real damage you deal per second of combat (everything counts: shots, crits, companions, explosions, status effects), how many hits you take per minute, and your stats and items. From that it works out your RUN LEVEL (1-10) and each boss adjusts when it appears: at a normal level (5) it comes as designed; if you're strong or “broken”, with much more health, pace and damage, and if you're struggling, weaker and slower. Health goes from ×0.5 to ×10.
- Warnings
- Before each big hit, the floor warns you: a line for charges and beams, a filling circle for things falling from the sky, a cone for flamethrowers, a ring with a bright gap to slip through, half the room or a column. When the warning fills up, it strikes.
- Warning colours
- Red: Hit coming right away · Yellow: Cone or gap to slip through · Violet: Zone that stays on the ground
- Phases
- Floor bosses switch to their second attack set at half health; mega bosses Mega Evolve at 70 % and enter a final phase at 35 %
- Reward
- A boss item, the trapdoor down, and sometimes a rift to the Distortion or Celestial Room
Viridian Forest floor 1
Boss arena: Bushes that slow you and hide shots.
Butterfree
Bug Wing dust
170 base health
- Signature move
- Stun Spore
- Attacks
- Floor zones, 2-arm spiral, Ring of 10 shots, 3 homing shots
- Second phase
- Gust, Floor zones, Summons 3 Caterpie, Ring of 14 shots
Pinsir
Bug Pincers of the forest
210 base health
- Signature move
- Guillotine
- Attacks
- 1 chained charges, Fan of 3 shots, Take Down
- Second phase
- 2 chained charges, Volley, Summons 2 Caterpie
Scyther
Bug The green blade
230 base health
- Signature move
- Fury Cutter
- Attacks
- 2 chained charges, Fan of 3 shots, 3 chained charges, Fan of 5 shots
- Second phase
- 3 chained charges, Volley, 2 chained charges, Ring of 8 shots
Venomoth
Bug The toxic moth
200 base health
- Signature move
- Poison Powder
- Attacks
- Puddle checkerboard, 3 homing shots, Fan of 5 shots, Poison gas ring (8)
- Second phase
- Puddle checkerboard, Teleport, Poison gas ring (10), 4 homing shots, Summons 1 Venonat
Vileplume
Grass Carnivorous flower
240 base health
- Signature move
- Petal Dance
- Attacks
- 2-arm spiral, Ring of 8 shots, Fan of 5 shots, Summons 2 Oddish
- Second phase
- Beam, 3-arm spiral, Poison gas ring (12), Ring of 12 shots, Summons 3 Oddish
Mt. Moon floor 2
Boss arena: Stalactites fall when the ground shakes.
Onix
Rock Rock serpent
330 base health
- Signature move
- Dig
- Attacks
- Rain of 5 rocks, Take Down, Dig
- Second phase
- Dig, Rain of 8 rocks, Half-room sweep, Summons 1 Geodude, Ring of 8 shots
Golem
Rock The rolling stone
300 base health
- Signature move
- Roll
- Attacks
- Roll, Ring of 8 shots, Rain of 5 rocks
- Second phase
- Roll, Ring of 12 shots, Rain of 8 rocks
Kabutops
Rock The cutting fossil
320 base health
- Signature move
- Slash
- Attacks
- Spinning cross of 4, Take Down, Fan of 5 shots, Ring of 8 shots
- Second phase
- Spinning cross of 8, 2 chained charges, Summons 2 Kabuto, Ring of 12 shots
Steelix
Steel Steel serpent
380 base health
- Signature move
- Iron Tail
- Attacks
- Half-room sweep, Rain of 5 rocks, Take Down, Ring of 10 shots
- Second phase
- Double sweep, Rain of 8 rocks, Dig, Ring of 12 shots
Aerodactyl
Rock Terror of the skies
300 base health
- Signature move
- Wing Attack
- Attacks
- Dive, 3 homing shots, Take Down, Fan of 5 shots
- Second phase
- Dive, Rain of 8 rocks, 5 homing shots, Volley
Tyranitar
Rock Armor of the mountain
420 base health
- Signature move
- Sandstorm
- Attacks
- Sandstorm, Fan of 5 shots, Take Down, Rain of 8 rocks
- Second phase
- Walls with a gap, Sandstorm, Ring of 14 shots, Take Down, Volley
Pokémon Tower floor 3
Boss arena: The candles go out.
Gengar
Ghost The shadow prankster
380 base health
- Signature move
- Shadow Ball
- Attacks
- 2 clones, Teleport, Fan of 5 shots, 2 homing shots
- Second phase
- Ambush, 2 clones, Ring of 12 shots, Summons 2 Gastly, Volley
Marowak
Ground The bone keeper
340 base health
- Signature move
- Bonemerang
- Attacks
- Boomerang bones, Ring of 8 shots, Take Down, Fan of 3 shots
- Second phase
- Boomerang bones, Marked rain, Take Down, Summons 2 Cubone
Dusknoir
Ghost Guide of souls
400 base health
- Signature move
- Shadow Punch
- Attacks
- Hands from the ground, Teleport, 3 homing shots, Ring of 10 shots
- Second phase
- Hands from the ground, Teleport, Poison gas ring (12), Summons 3 Duskull, 5 homing shots
Chandelure
Ghost The lamp that snuffs out lives
360 base health
- Signature move
- Will-O-Wisp
- Attacks
- Will-o'-wisps, Ring of 10 shots, 4 homing shots, Teleport
- Second phase
- Haze, Will-o'-wisps, Laser, Ring of 14 shots, Summons 3 Litwick
Spiritomb
Ghost The 108 souls
340 base health
- Signature move
- Spite
- Attacks
- Wall with a gap, Teleport, Ring of 12 shots, Summons 2 Duskull
- Second phase
- Walls with a gap, Teleport, Poison gas ring (14), 5 homing shots, Summons 3 Shuppet
Cinnabar Mansion floor 4
Boss arena: Fire grates in turns.
Muk
Poison The all-devouring sludge
440 base health
- Signature move
- Sludge
- Attacks
- Floor zones, Fan of 5 shots, Ring of 10 shots, Summons 2 Grimer
- Second phase
- Floor zones, Fan of 7 shots, Summons 3 Grimer, Ring of 14 shots, Take Down
Weezing
Poison The poison cloud
380 base health
- Signature move
- Smoke Blast
- Attacks
- Haze, Poison gas ring (12), Fan of 5 shots, Take Down
- Second phase
- Haze, Self-Destruct, Poison gas ring (16), Summons 3 Koffing, Volley
Arcanine
Fire The legend of the East
420 base health
- Signature move
- Extreme Speed
- Attacks
- 3 chained charges, Fan of 5 shots, Take Down
- Second phase
- 4 chained charges, Volley, Ring of 12 shots, Summons 2 Growlithe
Magmortar
Fire The volcanic cannon
420 base health
- Signature move
- Flamethrower
- Attacks
- Flamethrower, Fan of 5 shots, Volley, Ring of 10 shots
- Second phase
- Flamethrower, Floor zones, Ring of 16 shots, Summons 2 Slugma
Electivire
Electric The thunder fist
400 base health
- Signature move
- Thunder Punch
- Attacks
- Lightning columns, Take Down, Volley, Fan of 5 shots
- Second phase
- Spinning cross of 8, Lightning columns, Laser, Summons 2 Magnemite
Weak to: Ground
Houndoom
Dark The hellhound
380 base health
- Signature move
- Fire Fang
- Attacks
- Ring of fire, Take Down, Abanico de 5 shots
- Second phase
- Ring of fire, 2 chained charges, Volley, Ring of 12 shots, Summons 2 Houndour
Cerulean Cave floor 5
Boss arena: Psychic runes under your feet.
Mewtwo
Psychic The created Pokémon
720 base health
- Signature move
- Psycho Boost
- Attacks
- Wave with a gap, Teleport, 3 homing shots, Fan of 5 shots
- Second phase
- Barrier, Wave with a gap, Teleport, Laser, 2-arm spiral, 4 homing shots
Deep floors 6 and below
From floor 6 the five areas repeat with new names (Shadow Forest, Lunar Grotto, Cursed Tower, Ruined Mansion, Cerulean Abyss) and any floor boss can show up, plus these five. Mewtwo and Mew guard floors 15 and 25.
Gyarados
Water Fury of the sea
520 base health
- Signature move
- Hydro Pump
- Attacks
- Hydro Pump, Take Down, Ring of 12 shots
- Second phase
- Dragon Dance, Hydro Pump, 3 chained charges, Ring of 16 shots, Laser, Volley
Salamence
Dragon The sky dragon
540 base health
- Signature move
- Outrage
- Attacks
- 3 chained charges, Fan of 7 shots, 4 homing shots
- Second phase
- 4 chained charges, Volley, Ring of 16 shots, Dive
Garchomp
Dragon The land shark
560 base health
- Signature move
- Earthquake
- Attacks
- Earthquake, Take Down, Fan of 5 shots
- Second phase
- Dig, Earthquake, Rain of 10 rocks, Take Down
Metagross
Steel The iron mind
600 base health
- Signature move
- Meteor Mash
- Attacks
- Sky drop, Teleport, 4 homing shots, Rain of 8 rocks
- Second phase
- Sky drop, Laser, Rain of 12 rocks, Ring of 16 shots
Dragonite
Dragon The gentle dragon
580 base health
- Signature move
- Hyper Beam
- Attacks
- Hyper Beam, Take Down, Ring of 12 shots, 4 homing shots
- Second phase
- Crossed Hyper Beams, Dive, Ring of 16 shots, Volley
Mew
Psychic The origin of all
500 base health
- Signature move
- Transform
- Attacks
- Copies a move, Teleport, Ring of 12 shots, 3 homing shots
- Second phase
- Copies two moves, Copies a move, Teleport, Laser, Ring of 18 shots
Armored Mewtwo floor 30
Five pieces that break separately depending on where you hit: each one costs it an attack. They crack before breaking and stay on the ground. At 60 % the rest fly off, at 30 % it breaks free and at 15 % it Mega Evolves into Mega Mewtwo Y.
- Helmet
- Aims worse without it
- Pauldrons
- Without them, no Double Cannon
- Tubes
- Without them, no Psi Missiles
- Breastplate
- While worn, it takes 40 % less damage
Armored Mewtwo
Psychic The ultimate weapon
1,650 base health
- Signature move
- Twin Cannon
- Attacks
- Twin Cannon, Psi Missiles, Barrier, Teleport, Fan of 7 shots
- Second phase
- Wave with a gap, Spinning cross of 4, Overflow, Teleport, Laser, 6 homing shots
- Final phase
- Wave with a gap, Future Sight, Final blow, Teleport, 3-arm spiral, 7 homing shots
Armored Mewtwo awaits on floor 30. Defeat it and a cutscene ends Classic mode, the Mega banner opens and you choose: end with the win or continue in endless mode.
Mega bosses every 10 floors
Every 10 floors, a shiny mega boss picked by the run (no repeats): it starts in its normal form, Mega Evolves in front of you at 70 % and enters its final phase at 35 %. Each species has its own mega attack. Double reward (two rounds of items and Mega Tickets). Fixed milestones: Mega Rayquaza on 50, the Mega Latias and Mega Latios duo on 80 and Mega Mewtwo Y on 100. From floor 40 they have affixes (Armored, Swift, Summoner, Mirror, Vampire, Enraged).
- Affix: Armored
- Shield you must break first
- Affix: Swift
- Moves and attacks faster
- Affix: Summoner
- Calls young of its type each phase
- Affix: Mirror
- Reflects one in ten shots
- Affix: Vampire
- Heals when it hits you
- Affix: Enraged
- Starts in phase 2
| Mega boss | Type | Health | Signature move | Attacks | Final phase | Weak to |
|---|---|---|---|---|---|---|
 Mega Charizard X | Fire | 1,022 | Flare Blitz | Take Down, Fan of 5 shots, Volley | Flare Blitz, Flamethrower, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Water Rock Ground |
 Mega Alakazam | Psychic | 990 | Future Sight | Teleport, 4 homing shots, Ring of 12 shots | Future Sight, Barrier, Wave with a gap, Teleport, Laser, Ring of 16 shots, 6 homing shots, Volley | Ghost Bug Dark |
 Mega Slowbro | Water | 981 | Calm Mind | Teleport, 4 homing shots, Ring of 12 shots | Barrier, Hydro Pump, Wave with a gap, Teleport, Laser, Ring of 16 shots, 6 homing shots, Volley | Electric Grass |
 Mega Gengar | Ghost | 990 | Mean Look | 2 clones, Teleport, 4 homing shots, Ring of 12 shots | 3 clones, Ambush, Hands from the ground, 2 clones, Teleport, Laser, Ring of 16 shots, 6 homing shots, Volley | Ghost Dark |
 Mega Kangaskhan | Normal | 981 | Parental Bond | Take Down, Fan of 5 shots, Volley | 2 chained charges, 1 clones, Earthquake, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Fighting |
 Mega Aerodactyl | Rock | 1,004 | Wing Attack | Dive, Take Down, Rain of 8 rocks, Fan of 5 shots | Dive, Marked rain, Take Down, Rain of 12 rocks, Ring of 14 shots, Volley | Water Grass Ground Fighting Steel |
 Mega Mewtwo Y | Psychic | 1,451 | Psycho Boost | Wave with a gap, Teleport, 4 homing shots, Ring of 12 shots | Wave with a gap, Future Sight, 3-arm spiral, Barrier, Teleport, Laser, Ring of 16 shots, 6 homing shots, Volley | Ghost Bug Dark |
 Mega Steelix | Steel | 1,000 | Iron Tail | Half-room sweep, Take Down, Rain of 8 rocks, Fan of 5 shots | Double sweep, Dig, Half-room sweep, Take Down, Rain of 12 rocks, Ring of 14 shots, Volley | Fire Ground Fighting |
 Mega Houndoom | Dark | 990 | Flamethrower | Ring of fire, Take Down, Fan of 5 shots, Volley | Flamethrower, Ring of fire, 2 chained charges, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Bug Fighting Fairy |
 Mega Sceptile | Grass | 1,019 | Leaf Blade | Teleport, 4 homing shots, Ring of 12 shots | 3 chained charges, 3-arm spiral, Teleport, Laser, Ring of 16 shots, 6 homing shots, Volley | Fire Poison Bug Flying Ice |
 Mega Gardevoir | Psychic | 1,007 | Moonblast | Teleport, 4 homing shots, Ring of 12 shots | Future Sight, Barrier, 3-arm spiral, Teleport, Laser, Ring of 16 shots, 6 homing shots, Volley | Ghost Bug Dark |
 Mega Sableye | Dark | 876 | Foul Play | Take Down, Fan of 5 shots, Volley | Ambush, 2 clones, Hands from the ground, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Bug Fighting Fairy |
 Mega Mawile | Steel | 876 | Play Rough | Take Down, Rain of 8 rocks, Fan of 5 shots | 2 chained charges, Double sweep, Take Down, Rain of 12 rocks, Ring of 14 shots, Volley | Fire Ground Fighting |
 Mega Manectric | Electric | 966 | Wild Charge | Take Down, Fan of 5 shots, Volley | 3 chained charges, Lightning columns, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Ground |
 Mega Sharpedo | Water | 952 | Aqua Jet | Teleport, 4 homing shots, Ring of 12 shots | 4 chained charges, Hydro Pump, Teleport, Laser, Ring of 16 shots, 6 homing shots, Volley | Electric Grass |
 Mega Camerupt | Fire | 952 | Eruption | Take Down, Fan of 5 shots, Volley | Marked rain, Floor zones, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Water Rock Ground |
 Mega Altaria | Dragon | 981 | Hyper Voice | Take Down, Fan of 5 shots, Volley | Wave with a gap, Dive, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Dragon Ice Fairy |
 Mega Banette | Ghost | 947 | Curse | Teleport, 4 homing shots, Ring of 12 shots | Curse, Hands from the ground, Teleport, Laser, Ring of 16 shots, 6 homing shots, Volley | Ghost Dark |
 Mega Absol | Dark | 957 | Night Slash | Take Down, Fan of 5 shots, Volley | 3 chained charges, Haze, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Bug Fighting Fairy |
 Mega Glalie | Ice | 971 | Freeze-Dry | Teleport, 4 homing shots, Ring of 12 shots | Marked rain, Spinning cross of 8, Self-Destruct, Teleport, Laser, Ring of 16 shots, 6 homing shots, Volley | Fire Rock Fighting Steel |
 Mega Latias | Dragon | 1,085 | Luster Purge | Take Down, Fan of 5 shots, Volley | Dive, Wave with a gap, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Dragon Ice Fairy |
 Mega Latios | Dragon | 1,085 | Mist Ball | Take Down, Fan of 5 shots, Volley | Dive, Hyper Beam, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Dragon Ice Fairy |
 Mega Rayquaza | Dragon | 1,451 | Dragon Ascent | Take Down, Fan of 5 shots, Volley | Sky drop, Dive, Hyper Beam, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Dragon Ice Fairy |
 Mega Lopunny | Normal | 971 | High Jump Kick | Take Down, Fan of 5 shots, Volley | Sky drop, 2 chained charges, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Fighting |
 Mega Lucario | Fighting | 1,014 | Aura Sphere | Take Down, Fan of 5 shots, Volley | 3 chained charges, Wave with a gap, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Psychic Flying Fairy |
 Mega Gallade | Psychic | 1,007 | Psycho Cut | Teleport, 4 homing shots, Ring of 12 shots | 3 chained charges, Spinning cross of 4, Teleport, Laser, Ring of 16 shots, 6 homing shots, Volley | Ghost Bug Dark |
 Mega Excadrill | Ground | 998 | Drill Run | Take Down, Rain of 8 rocks, Fan of 5 shots | Dig, Marked rain, Take Down, Rain of 12 rocks, Ring of 14 shots, Volley | Water Grass Ice |
 Mega Scrafty | Dark | 979 | Drain Punch | Take Down, Fan of 5 shots, Volley | 3 chained charges, Earthquake, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Bug Fighting Fairy |
 Mega Eelektross | Electric | 1,004 | Electroweb | Take Down, Fan of 5 shots, Volley | Electroweb, Lightning columns, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Ground |
 Mega Floette | Fairy | 867 | Eternal Light | Teleport, 4 homing shots, Ring of 12 shots | 3-arm spiral, Floor zones, Hyper Beam, Teleport, Laser, Ring of 16 shots, 6 homing shots, Volley | Poison Steel |
 Mega Dragalge | Poison | 984 | Dragon Pulse | Teleport, 4 homing shots, Ring of 12 shots | Puddle checkerboard, Hydro Pump, Teleport, Laser, Ring of 16 shots, 6 homing shots, Volley | Psychic Ground |
 Mega Hawlucha | Fighting | 990 | Flying Press | Take Down, Fan of 5 shots, Volley | Sky drop, Dive, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Psychic Flying Fairy |
 Mega Zygarde | Dragon | 1,085 | Thousand Waves | Take Down, Fan of 5 shots, Volley | Earthquake, Walls with a gap, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Dragon Ice Fairy |
 Mega Diancie | Rock | 1,085 | Power Gem | Take Down, Rain of 8 rocks, Fan of 5 shots | Marked rain, Barrier, Walls with a gap, Take Down, Rain of 12 rocks, Ring of 14 shots, Volley | Water Grass Ground Fighting Steel |
 Mega Drampa | Dragon | 976 | Draconic Roar | Take Down, Fan of 5 shots, Volley | Crossed Hyper Beams, Wave with a gap, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Dragon Ice Fairy |
 Mega Zeraora | Electric | 1,085 | Plasma Fists | Take Down, Fan of 5 shots, Volley | 4 chained charges, Lightning columns, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Ground |
 Mega Tatsugiri | Dragon | 966 | Stratagem | Take Down, Fan of 5 shots, Volley | 3 clones, Hydro Pump, Take Down, Volley, Ring of 14 shots, Fan of 7 shots | Dragon Ice Fairy |
Fixed milestones: Mega Rayquaza on floor 50, Mega Latias and Mega Latios on 80, Mega Mewtwo Y on 100. Beating Armored Mewtwo, Mega Rayquaza, the Eon duo and Mega Mewtwo Y gives a trophy on your profile.
Darkrai Distortion Room
Once per run, with a 10 % chance, Darkrai offers no deals: it attacks you. Once defeated, it drops a Charcoal. See the deals Darkrai sells the other nine times out of ten.
Darkrai
Dark Lord of nightmares
240 base health
- Signature move
- Dark Void
- Attacks
- Floor zones, Teleport, 3 homing shots, Ring of 8 shots
- Second phase
- Haze, Floor zones, Teleport, Volley, 5 homing shots
Indigo League and Mt. Silver
Two more modes are in the game but closed to most players: the Indigo League (Kanto's 8 gyms with 6 waves each, then the Elite Four and Champion Blue) is testers-only, and Mt. Silver needs the Shiny Charm, which you get for completing all 971 Pokémon of the Pokédex. Their leaders:
| Gym | Leader | Type | Boss | Health | Weak to |
|---|---|---|---|---|---|
| Pewter City | Brock | Rock | Onix | 330 | Water Grass |
| Cerulean City | Misty | Water |  Starmie | 260 | Grass Electric |
| Vermilion City | Lt. Surge | Electric |  Raichu | 280 | Ground |
| Celadon City | Erika | Grass | Vileplume | 240 | Fire Ice Flying |
| Fuchsia City | Koga | Poison | Weezing | 380 | Ground Psychic |
| Saffron City | Sabrina | Psychic |  Alakazam | 300 | Ghost Dark Bug |
| Cinnabar Island | Blaine | Fire | Arcanine | 420 | Water Ground Rock |
| Viridian City | Giovanni | Ground |  Rhydon | 380 | Water Grass Ice |
| Elite Four | Lorelei | Ice |  Lapras | 420 | Fire Fighting Rock |
| Elite Four | Bruno | Fighting |  Machamp | 440 | Psychic Flying |
| Elite Four | Agatha | Ghost | Gengar | 380 | Ghost Dark |
| Elite Four | Lance | Dragon | Dragonite | 580 | Ice Dragon |
| Champion | Blue | Mixed |   Pidgeot, Gyarados, Charizard | 380 / 520 / 520 | |
| Mt. Silver | Mt. Silver Foothills | Tyranitar, Steelix, Aerodactyl | |||
| Mt. Silver | Mt. Silver Cave | Dragonite, Gyarados, Salamence, Garchomp | |||
| Mt. Silver | Mt. Silver Summit |  Pikachu |
At the summit waits Red with Pikachu, Espeon, Snorlax, Venusaur, Charizard, Blastoise.